Preventing stroke: does race/ethnicity matter?
نویسندگان
چکیده
Stroke, the third leading cause of death in the United States, is also the chief cause of neurological disability in the elderly. Lifetime risk of stroke at age 65 years is estimated to be 1 in 5 in women and 1 in 6 in men in the Framingham Study population.1 Despite improvements in management of the acute stroke and in rehabilitation poststroke, it is clear that prevention holds the key to decreasing the toll of cerebrovascular disease. In recent years, it has become increasingly clear that clinically inapparent strokes detected on magnetic resonance scan of the brain, so-called “silent” strokes, exert a discernible impact on brain function.2 Measurable reduction in cognitive performance that leads to vascular cognitive impairment, depressed mood, and impaired gait are consequences of these “silent” strokes.3 In addition, persons harboring these infarcts and a large burden of white-matter hyperintensities are predisposed to develop clinically apparent cerebral infarctions. Further, the presence of elevated levels of stroke risk factors exerts a measurable effect on brain structure and function, which results in reduced total cerebral volume and an increased presence and volume of white-matter hyperintensities on magnetic resonance scan of the brain, as well as reduced cognitive performance, particularly on tests of executive function.4
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When Race/Ethnicity Matters More Than Size Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2007 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi: 10.1161/STROKEAHA.107.488817 2007;38:2405-2406; originally published online August 2, 2007; Stroke. http://stroke.ahajournals.org/conten...
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ورودعنوان ژورنال:
- Circulation
دوره 116 19 شماره
صفحات -
تاریخ انتشار 2007